Related Experiment Video
Updated: Jun 25, 2026

Transformation of Probiotic Yeast and Their Recovery from Gastrointestinal Immune Tissues Following Oral Gavage in Mice
Published on: February 8, 2016
DNA-based gels for oral delivery of probiotic bacteria
Benjamas Jonganurakkun1, Yoshinobu Nodasaka, Nobuo Sakairi
1Graduate School of Environmental Science, Hokkaido University, Sapporo 060-0810, Japan.
Abstract:
A single-stranded DNA, readily extracted from industrial discarded salmon milt, was used to prepare hydrogels and complex gels by cross-linking with gelatin and kappa-carrageenan, for the oral delivery of probiotic bacteria. The complex gels showed a higher protective capability over the hydrogels for approximately one log scale. However, the hydrogels were more stable during storage at 4 degrees C. The Lactobacillus and Lactococcus due to protection of the hydrogels could better tolerate to acid than the Bifidobacterium. Furthermore, food-graded hydrogels were prepared and optimized to a similar protective capability for future applications.
More Related Videos
Related Concept Videos
Genomic DNA in Prokaryotes
Genomic Diversity in Bacteria
Although bacterial genomes are much...
Oral Drug Delivery Systems: Introduction
Probiotics

