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Antiretroviral medication errors in a national medication error database.

Jennifer Gray1, Rodney W Hicks, Cristi Hutchings

  • 1School of Nursing, University of Texas at Arlington, UTA Box 19407, Arlington, TX 76019-0407, USA. jgray@uta.edu

AIDS Patient Care and Stds
|December 27, 2005
PubMed
Summary

Medication errors involving antiretroviral drugs, crucial for HIV treatment, can cause harm. Analysis of 400 errors found dispensing issues and wrong doses/medications were most common, highlighting a need for improved safety processes.

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Area of Science:

  • Pharmacology
  • Patient Safety
  • Public Health

Background:

  • Antiretroviral medications have significantly improved outcomes for individuals with HIV.
  • Medication errors involving these drugs pose a risk of harm, counteracting treatment benefits.

Purpose of the Study:

  • To analyze medication errors involving HIV antiretroviral products.
  • To identify the phases, types, and contributing factors of these errors.

Main Methods:

  • Analysis of 400 medication errors reported to the MEDMARX national program.
  • Categorization of errors by phase, type, and involved antiretroviral product.

Main Results:

  • 3% of analyzed antiretroviral medication errors resulted in harm.

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  • The dispensing phase accounted for 45% of errors, with wrong dose (37.5%) and wrong medication (32%) being most frequent.
  • Lamivudine was the most implicated product; community hospitals showed higher prescribing errors than teaching hospitals. Similar drug names contributed to errors.

    • Conclusions:

    • Dispensing errors are a significant concern in antiretroviral medication use.
    • Healthcare organizations need robust systems for order clarification and up-to-date drug references.
    • Clear prescribing practices, avoiding abbreviations, and error reporting are vital for enhancing patient safety in HIV treatment.