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Updated: Aug 14, 2026
Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development
Published on: October 30, 2013
Developing innovative strategies for advanced transitional cell carcinoma of the bladder
Camillo F Pollera1, Fabrizio Nelli
1Department of Medical Oncology, Presidio Ospedaliero Centrale di Belcolle, ASL di Viterbo, Strada Sammartinese snc, 01100, Viterbo, Italy. cfpollera@oncologiaviterbo.it
Abstract:
Several improvements in the treatment of advanced transitional cell malignancies have been provided by clinical trials in the past 10 years. Nonetheless, there are conflicting results regarding the effect of perioperative chemotherapy of muscle-invasive disease and new cytotoxic agents in the metastatic setting. The authors will discuss the results of major clinical trials and examine developing targeted-oriented treatment strategies.
