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Related Experiment Videos

X-ray volume imaging in bladder radiotherapy verification.

Ann M Henry1, Julia Stratford, Claire McCarthy

  • 1Academic Department of Radiation Oncology, University of Manchester, Manchester, United Kingdom. amhenry@doctors.net.uk

International Journal of Radiation Oncology, Biology, Physics
|December 27, 2005
PubMed
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X-ray volume imaging (XVI) accurately verifies 3D bladder radiotherapy delivery, ensuring clinical target volume coverage. This technology enables image-guided interventions to minimize geographic miss and normal tissue toxicity.

Area of Science:

  • Radiation oncology
  • Medical imaging
  • Radiotherapy physics

Background:

  • Bladder radiotherapy requires precise targeting to maximize tumor control and minimize toxicity.
  • Accurate verification of daily treatment setup is crucial for effective radiotherapy.
  • X-ray volume imaging (XVI) offers potential for real-time, 3D imaging during radiotherapy delivery.

Purpose of the Study:

  • To evaluate the clinical usefulness of X-ray volume imaging (XVI) for verifying bladder radiotherapy.
  • To quantify the geometric errors associated with bladder radiotherapy delivery using XVI.

Main Methods:

  • Twenty patients undergoing conformal bladder radiotherapy were studied.
  • X-ray volume images (XVI) and electronic portal images (EPIs) were acquired during the initial fractions and weekly.

Related Experiment Videos

  • XVI data were co-registered with planning CT scans for 3D assessment of clinical target volume coverage and interfraction bladder volume changes.

    • Main Results:

    • The bladder wall was clearly visualized on coronal XVI, enabling accurate 3D treatment verification.
    • Clinical target volume coverage was maintained within the planning target volume in 93.5% of fractions.
    • While most bladders showed consistent volumes, 25% exhibited predictable volume changes based on early XVIs. Bony setup errors were comparable between XVI and EPI.

    Conclusions:

    • Coronal XVI is effective for verifying 3D bladder radiotherapy delivery.
    • XVI facilitates image-guided interventions to reduce geographic miss and normal tissue toxicity in bladder cancer patients.