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Keratoprosthesis: the Dohlman-Doane device.

James V Aquavella1, Ying Qian, Gregory J McCormick

  • 1Department of Ophthalmology, University of Rochester Eye Institute, 601 Elmwood Avenue, Box 659, Rochester, NY 14642, USA. james_aquavella@urmc.rochester.edu

American Journal of Ophthalmology
|December 27, 2005
PubMed
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The Dohlman-Doane type I keratoprosthesis offers visual rehabilitation for patients with poor prognosis for traditional corneal transplants. This artificial cornea implant demonstrated effectiveness with minimal complications, restoring vision in challenging cases.

Area of Science:

  • Ophthalmology
  • Corneal Surgery
  • Visual Prosthetics

Background:

  • Penetrating keratoplasty (corneal transplant) has limitations in patients with multiple graft failures or poor ocular conditions.
  • Alternative solutions are needed for visual rehabilitation in high-risk corneal disease patients.

Purpose of the Study:

  • To evaluate the Dohlman-Doane type I keratoprosthesis as a viable option for visual restoration.
  • To assess the safety and efficacy of this artificial cornea in patients unsuitable for conventional corneal transplants.

Main Methods:

  • A retrospective study included 25 patients with a history of failed corneal grafts or poor prognosis for standard keratoplasty.
  • The Dohlman-Doane type I keratoprosthesis was implanted, and patients were monitored for visual acuity, complications, and device integrity.

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Main Results:

  • The keratoprosthesis was successfully retained in all patients without dislocation or extrusion.
  • No cases of endophthalmitis or surface infection were reported.
  • Significant visual acuity improvement was observed, with final acuity ranging up to 20/25, though retroprosthetic membranes occurred in some cases.

Conclusions:

  • The Dohlman-Doane type I keratoprosthesis is a safe and effective option for visual rehabilitation in patients with poor prognosis for penetrating keratoplasty.
  • Routine implantation and maintenance of this artificial cornea can lead to successful visual outcomes in challenging corneal conditions.