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Sweet's syndrome responding to cyclosporin
J F Bourke1, J Berth-Jones, R A Graham-Brown
1Department of Dermatology, Leicester Royal Infirmary, U.K.
The British Journal of Dermatology
|July 1, 1992
Summary
This study shows cyclosporin effectively treats Sweet's syndrome, a skin condition. Cyclosporin works by affecting immune cells like T-lymphocytes, neutrophils, and monocytes.
Area of Science:
- Dermatology
- Immunology
Background:
- Sweet's syndrome is an acute febrile neutrophilic dermatosis.
- Treatment options for Sweet's syndrome can be limited.
Observation:
- A case of Sweet's syndrome was treated with cyclosporin at a dosage of 4 mg/kg/day.
- The patient showed a positive response to the cyclosporin treatment.
Findings:
- Cyclosporin demonstrated efficacy in managing Sweet's syndrome.
- The study discusses potential mechanisms of cyclosporin's action, including its effects on T-lymphocytes, neutrophils, and monocytes.
Implications:
- Cyclosporin may be a viable therapeutic option for Sweet's syndrome.
- Further research into cyclosporin's immunomodulatory effects in dermatoses is warranted.