Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Obstructive uropathy.

Amy Becker1, Michel Baum

  • 1Department of Pediatrics, University of Texas Southwestern Medical Center at Dallas, Dallas, 5323 Harry Hines Blvd,. Texas 75390-9063, USA.

Early Human Development
|December 27, 2005
PubMed
Summary

Antenatal hydronephrosis, detected via ultrasound, requires postnatal evaluation. Prompt diagnosis and management of obstructive uropathy are crucial to prevent chronic kidney disease in infants.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Comparative Environmental Impact Analysis of Screening Tests for Colorectal Cancer.

medRxiv : the preprint server for health sciences·2025
Same author

Improved metal suppression using new generation low-field MRI: a biophantom feasibility study.

Skeletal radiology·2024
Same author

Ghrelin enhances tubular magnesium absorption in the kidney.

Frontiers in physiology·2024
Same author

Hemolytic uremic syndrome as a rare complication in a case of Castleman disease.

Pediatric blood & cancer·2024
Same author

Implementing an exclusive human milk diet for preterm infants: real-world experience in diverse NICUs.

BMC pediatrics·2023
Same author

Editorial: Intensive care unit nephrology.

Current opinion in pediatrics·2023

Area of Science:

  • Pediatric Nephrology
  • Fetal Medicine
  • Urology

Background:

  • Routine second-trimester ultrasounds increasingly detect antenatal hydronephrosis in infants.
  • Postnatal evaluation is recommended for renal pelvic diameter >5 mm, typically with ultrasound and voiding cystourethrogram (VCUG).
  • Diverse etiologies of obstructive uropathy exist, including UPJ obstruction, UVJ obstruction, posterior urethral valves (PUV), prune belly syndrome, and VUR.

Purpose of the Study:

  • To highlight the significance of antenatal hydronephrosis diagnosis.
  • To underscore the potential for tubular damage and nephron loss from obstructive uropathy.
  • To emphasize the risk of chronic renal insufficiency in neonates with significant nephron reduction or progressive renal damage.

Main Methods:

  • Review of current diagnostic and management guidelines for antenatal hydronephrosis.
  • Discussion of the etiological spectrum of obstructive uropathy.
  • Analysis of the long-term renal consequences of untreated or poorly managed obstructive uropathy.

Main Results:

  • Antenatal hydronephrosis is a common finding requiring further investigation.
  • Obstructive uropathy can lead to significant renal damage, including tubular dysfunction and reduced nephron count.
  • While most neonates do not need immediate renal replacement therapy, chronic kidney disease can develop.

Conclusions:

  • Early identification and management of antenatal hydronephrosis are vital.
  • Understanding the causes and consequences of obstructive uropathy is essential for pediatric care.
  • Preventing progressive renal damage is key to long-term infant kidney health.

Related Experiment Videos