Primary peripheral lymphadenopathy in Jos, Nigeria
J O Obafunwa1, I N Olomu, N J Onyia
1Department of Pathology, Jos University Teaching Hospital, Plateau State, Nigeria.
Surgical biopsy specimens of 129 enlarged peripheral nodes seen at Jos University Teaching Hospital over a 3-year period were analyzed. Enlarged peripheral nodes due to primary sarcomas or carcinomas were excluded from the series. Tuberculosis and malignant lymphomas were diagnosed in 48.0% and 28.8% of the patients respectively. Amongst children aged 12 years and below, these diseases account for 50.0% and 30.0% childhood primary peripheral lymph node enlargement respectively. Non-diagnostic features were seen in 20.8% of patients. The cervical (53.0%), axillary (18.2%) and inguinal (7.4%) nodes are affected in that order. Regional lymph node involvement is the usual pattern.
Surgical biopsy specimens of 129 enlarged peripheral nodes seen at Jos University Teaching Hospital over a 3-year period were analyzed. Enlarged peripheral nodes due to primary sarcomas or carcinomas were excluded from the series. Tuberculosis and malignant lymphomas were diagnosed in 48.0% and 28.8% of the patients respectively. Amongst children aged 12 years and below, these diseases account for 50.0% and 30.0% childhood primary peripheral lymph node enlargement respectively. Non-diagnostic features were seen in 20.8% of patients. The cervical (53.0%), axillary (18.2%) and inguinal (7.4%) nodes are affected in that order. Regional lymph node involvement is the usual pattern.
Related Concept Videos
Peripheral Nervous System: Ganglia and Nerves
Nerves
The nerve is a bundle of axons that serves as the communication highway in the PNS. Each nerve is ensheathed in a protective layer of connective tissue called the epineurium. This outermost layer safeguards the nerve and supports the...
Lymphoid Cells and Tissues
Lymphoid cells consist of various types of immune system cells. These include B and T lymphocytes, which are responsible for producing antibodies and killing infected cells, respectively. Dendritic cells act as messengers between the innate and adaptive...
Primary Lymphoid Organs
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
Secondary Lymphoid Organs
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
Detailed Structure and Function of Lymph Nodes
From a histological perspective, lymph nodes can be split into two main areas: the superficial cortex and the deep medulla. The outer cortex is populated by dendritic cells, macrophages, and B lymphocytes, which are densely packed into follicles. When these B-lymphocytes are presented...
Leishmaniasis


