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Updated: Aug 14, 2026

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla
Published on: February 19, 2021
Magnetic resonance restricted diffusion resolution correlates with clinical improvement and response to treatment in
Joshua L Duckworth1, Jason S Hawley, Gerard Riedy
1Department of Neurology, Walter Reed Army Medical Center, Washington, DC 20307, USA.
Introduction:
A 34-year-old man presented with herpes simplex encephalitis (HSE), with magnetic resonance imaging (MRI) showing dense foci of restricted diffusion in the temporal lobe.
Case Report:
With treatment and clinical improvement, follow-up MRI done 8 days later showed complete resolution of the restricted diffusion abnormalities, whereas other MRI sequences suggested interval progression.
Discussion:
Restricted diffusion abnormalities on MRI in patients with HSE may be more sensitive to and correlate better with disease activity in HSE.

