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Published on: November 5, 2019
[Cluster of meningococcal diseases in Allgaeu -- strategies for intervention]
1Bayerisches Landesamt für Gesundheit und Lebensmittelsicherheit, Oberschleissheim. wolfgang.hautmann@lgl.bayern.de
Abstract:
In spring 2004 an accumulation of cases of invasive meningococcal disease was observed in the Allgaeu/Bavaria. Investigations of the isolates showed, that four cases in neighbouring municipalities of the district Oberallgaeu were caused by an identical strain of serogroup C. The particular strain was a rare variant of the so called ET-15 clone, which had caused several outbreaks of severe meningococcal disease among young people in the past, for example in Rottal/Inn (1998), Karlsruhe (1999 - 2000) and Schwerte (2003). The involved health authorities had to decide, which intervention strategies were reasonable and appropriate to the given situation. An epidemiological assessment of the situation was made by the Bavarian Health and Food Safety Authority (LGL) using the recommendations of the permanent immunization committee at the Robert Koch-Institute and of the Advisory Committee on Immunization Practices of the Centers for Disease Control and Prevention (CDC) . The LGL together with the Robert Koch-Institute and the national meningococcal reference centre concluded that the situation fulfilled the criteria for a vaccination indication in accordance with section sign 20 Abs. 5 of the infectious disease control act (Infektionsschutzgesetz, IfSG). On the basis of this assessment the responsible regional health authority issued a public recommendation for vaccination and the district health authority of the Oberallgaeu was assigned to implement a vaccination campaign. The Oberallgaeu health authority offered vaccination sessions to the public in the concerned communities. The target group comprised babies, children, young people and adults up to twenty years, who lived in the concerned communities in the northern part of Oberallgaeu, as well as close contacts of cases and members of the above age group, who had visited communal facilities in the communities concerned. Our report describes the implementation of the vaccination campaign.
Insights
An invasive meningococcal disease outbreak in Bavaria prompted a public vaccination campaign. Health authorities recommended vaccination for individuals up to age twenty in affected areas to control the rare ET-15 clone strain.
Area of Science:
- Epidemiology
- Infectious Disease Control
- Public Health
Context:
- An increase in invasive meningococcal disease (IMD) cases was noted in Bavaria in spring 2004.
- Four cases in the Oberallgaeu district were linked to a rare variant of the ET-15 clone, a strain previously associated with IMD outbreaks.
Purpose:
- To describe the epidemiological assessment and implementation of a public vaccination campaign in response to a localized IMD outbreak.
- To evaluate the public health response to a specific meningococcal serogroup C strain.
Summary:
- An epidemiological assessment identified the ET-15 clone as the cause of IMD cases in Oberallgaeu, Bavaria.
- Based on recommendations from national and international immunization committees, a vaccination indication was established.
- A public vaccination campaign targeted individuals up to twenty years old in affected communities, including close contacts and those using communal facilities.
Impact:
- The vaccination campaign aimed to control the spread of the specific IMD strain within the identified high-risk population.
- This case study highlights the public health decision-making process and intervention strategies for managing localized infectious disease outbreaks.
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