Modelling variability in hospital bed occupancy

Related Experiment Videos

Gary W Harrison1, Andrea Shafer, Mark Mackay

  • 1Department of Mathematics, College of Charleston, Charleston, SC, USA. harrisong@cofc.edu

A stochastic version of the Harrison-Millard multistage model of the flow of patients through a hospital division is developed in order to model correctly not only the average but also the variability in occupancy levels, since it is the variability that makes planning difficult and high percent occupancy levels increase the risk of frequent overflows. The model is fit to one year of data from the medical division of an acute care hospital in Adelaide, Australia. Admissions can be modeled as a Poisson process with rates varying by day of the week and by season. Methods are developed to use the entire annual occupancy profile to estimate transition rate parameters when admission rates are not constant and to estimate rate parameters that vary by day of the week and by season, which are necessary for the model variability to be as large as in the data. The final model matches well the mean, standard deviation and autocorrelation function of the occupancy data and also six months of data not used to estimate the parameters. Repeated simulations are used to construct percentiles of the daily occupancy distributions and thus identify ranges of normal fluctuations and those that are substantive deviations from the past, and also to investigate the trade-offs between frequency of overflows and the percent occupancy for both fixed and flexible bed allocations. Larger divisions can achieve more efficient occupancy levels than smaller ones with the same frequency of overflows. Seasonal variations are more significant than day-of-the-week variations and variable discharge rates are more significant than variable admission rates in contributing to overflows.

Related Concept Videos

Probability Histograms01:17

Probability Histograms

A probability histogram is a visual representation of a probability distribution. Similar a typical histogram, the probability histogram consists of contiguous (adjoining) boxes. It has both a horizontal axis and a vertical axis. The horizontal axis is labeled with what the data represents. The vertical axis is labeled with probability. Each rectangular bar in the histogram is 1 unit wide, which suggests that the area under each bar equals the probability, P(x), where x is 1, 2, 3, and so on.
Model Approaches for Pharmacokinetic Data: Compartment Models01:14

Model Approaches for Pharmacokinetic Data: Compartment Models

Compartmental analysis is a widely adopted approach to characterizing drug pharmacokinetics. It uses compartment models that conceptualize the body as a collection of reversibly communicating compartments, each representing a group of tissues exhibiting similar drug distribution characteristics. The movement rate of the drug between these compartments is typically described by first-order kinetics.
Two primary types of compartment models are recognized: mammillary and catenary. The more...
Mechanistic Models: Compartment Models in Individual and Population Analysis01:23

Mechanistic Models: Compartment Models in Individual and Population Analysis

Mechanistic models are utilized in individual analysis using single-source data, but imperfections arise due to data collection errors, preventing perfect prediction of observed data. The mathematical equation involves known values (Xi), observed concentrations (Ci), measurement errors (εi), model parameters (ϕj), and the related function (ƒi) for i number of values. Different least-squares metrics quantify differences between predicted and observed values. The ordinary least squares (OLS)...
Residuals and Least-Squares Property01:11

Residuals and Least-Squares Property

The vertical distance between the actual value of y and the estimated value of y. In other words, it measures the vertical distance between the actual data point and the predicted point on the line
If the observed data point lies above the line, the residual is positive, and the line underestimates the actual data value for y. If the observed data point lies below the line, the residual is negative, and the line overestimates the actual data value for y.
The process of fitting the best-fit...
Variability: Analysis01:11

Variability: Analysis

Measures of variability are statistical metrics that reveal the dispersion pattern within a dataset. They are pivotal in biostatistics, providing insights into the heterogeneity within health and biological data. Variability signifies the degree to which data points diverge from one another, helping researchers understand the potential range of values and associated uncertainty within the data.
The range is a simple measure of variability, indicating the difference between the highest and...
Analysis of Population Pharmacokinetic Data01:12

Analysis of Population Pharmacokinetic Data

Analysis of population pharmacokinetic data involves studying the behavior of drugs within diverse populations to understand their pharmacokinetic parameters. Traditional pharmacokinetic methods typically involve collecting samples from a few individuals and estimating these parameters. While these methods are commonly used, they have limitations in capturing the variability in drug response among individuals or heterogeneous populations. Population pharmacokinetics is employed to address these...