Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Improvements in ion-trap chemical-ionization performance.

T Cairns1, K S Chiu, E Siegmund

  • 1Department of Health and Human Services, Food & Drug Administration, Office of Regulatory Affairs, Los Angeles, CA 90015.

Rapid Communications in Mass Spectrometry : RCM
|July 1, 1992
PubMed
Summary

A new scan function improves ion-trap chemical ionization by removing unwanted electron-ionization-like ions. This allows for direct comparison of ion-trap chemical ionization spectra with conventional instruments.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[The diagnostic validity of non-invasive pancreatic function tests--a meta-analysis].

Zeitschrift fur Gastroenterologie·2004
Same author

Inositol 1,4,5-trisphosphate formation, cytoplasmic calcium dynamics, and alpha-amylase secretion of pancreatic acini isolated from aged and chronically alcohol-fed rats.

International journal of pancreatology : official journal of the International Association of Pancreatology·2000
Same author

Different dosages of acetylsalicylic acid lead to adverse modifications of the reaction of rat pancreas to ethanol.

International journal of pancreatology : official journal of the International Association of Pancreatology·1998
Same author

Anomalous pancreatico-biliary junction--report of a new experimental model and review of the literature.

Journal of pediatric surgery·1996
Same author

[Modification of alcohol-induced pancreatic damage in rats by soybean diet].

Zeitschrift fur Gastroenterologie·1994
Same author

Multiresidue pesticide analysis by ion-trap mass spectrometry.

Rapid communications in mass spectrometry : RCM·1993

Area of Science:

  • Analytical Chemistry
  • Mass Spectrometry

Background:

  • Ion-trap mass spectrometry is a powerful analytical technique.
  • Chemical ionization (CI) is a soft ionization method used in mass spectrometry.
  • Electron ionization (EI) can produce fragment ions that complicate CI spectra.

Purpose of the Study:

  • To enhance the performance of ion-trap chemical ionization.
  • To eliminate electron-ionization-like (EI-like) ions from CI spectra obtained using ion traps.
  • To enable direct comparison of ion-trap CI spectra with those from conventional instruments.

Main Methods:

  • Implementation of a modified scan function in the ion-trap's automatic reaction control software.
  • Targeted rejection of EI-like ions generated during the initial phase of reaction ionization.

Related Experiment Videos

  • Acquisition and analysis of CI mass spectra.

    • Main Results:

    • Successful suppression of undesired EI-like ions in ion-trap CI spectra.
    • Production of 'pure' CI spectra free from concentration-dependent EI-like interferences.
    • Demonstration that improved ion-trap CI spectra are directly comparable to conventional CI spectra.

    Conclusions:

    • The modified scan function significantly improves ion-trap CI performance.
    • This advancement allows for more accurate and reliable CI analysis using ion traps.
    • The findings facilitate broader application and inter-instrument comparison of ion-trap CI data.