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Related Experiment Videos

Trace elements in full-term neonate hair.

R Moro1, G Gialanella, Y X Zhang

  • 1Dipartimento di Scienze Fisiche, Università di Napoli, Italy.

Journal of Trace Elements and Electrolytes in Health and Disease
|March 1, 1992
PubMed
Summary
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Trace element levels in newborn hair, measured by Proton Induced X-ray Emission (PIXE), showed no sex or gestational differences. Correlations between elements may reveal insights into human trace element metabolism.

Area of Science:

  • Pediatric Nutrition
  • Trace Element Analysis
  • Biomedical Science

Background:

  • Trace elements are essential for human health and development.
  • Hair analysis is a non-invasive method to assess long-term exposure to elements.
  • Understanding elemental profiles in newborns is crucial for assessing nutritional status and potential health risks.

Purpose of the Study:

  • To quantify the concentrations of 12 trace elements in the hair of 141 AGA newborn infants.
  • To investigate potential correlations between these trace elements.
  • To compare findings with existing literature and explore implications for trace element metabolism.

Main Methods:

  • Proton Induced X-ray Emission (PIXE) was utilized for simultaneous measurement of 12 trace elements.

Related Experiment Videos

  • Hair samples were collected from 141 AGA newborn infants at term.
  • Statistical analysis, including log-normal distribution and partial correlation, was performed.

    • Main Results:

    • Log-normal distributions were observed for all measured trace elements.
    • No significant differences in trace element concentrations were found concerning sex, gestational age, or body weight.
    • Significant correlations were identified between various trace elements, suggesting interconnected metabolic pathways. Zinc and copper levels were lower than reported in literature, while chromium and selenium were higher, aligning with some previous studies.

    Conclusions:

    • Hair trace element concentrations in newborns do not appear to be significantly influenced by sex, gestational age, or body weight.
    • Observed correlations among elements may provide insights into the regulatory mechanisms of trace element metabolism in humans.
    • While absolute concentrations can vary, elemental ratios and correlations might offer a more stable indicator of metabolic processes.