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FGDB: a comprehensive fungal genome resource on the plant pathogen Fusarium graminearum

Ulrich Güldener1, Gertrud Mannhaupt, Martin Münsterkötter

  • 1Chair of Genome Oriented Bioinformatics, Center of Life and Food Science, Technische Universität München, D-85350 Freising-Weihenstephan, Germany. u.gueldener@gsf.de

Nucleic Acids Research
|December 31, 2005
PubMed

Insights

The Fusarium graminearum Genome Database (FGDB) offers comprehensive genomic data for this major fungal pathogen affecting wheat and barley. It aids research through bioinformatics, functional classifications, and gene analysis tools.

Area of Science:

  • Plant Pathology
  • Mycology
  • Bioinformatics

Background:

  • Fusarium graminearum is a significant fungal pathogen impacting wheat and barley crops.
  • Accurate genomic information is crucial for understanding and combating F. graminearum.

Purpose of the Study:

  • To present the MIPS Fusarium graminearum Genome Database (FGDB) as a centralized resource.
  • To provide access to annotated genomic data for F. graminearum.

Main Methods:

  • Development of a comprehensive genome database (FGDB).
  • Automated and initial manual gene annotation of the F. graminearum genome.
  • Integration of bioinformatics analyses and functional protein classifications.
  • Organization of data using MIPS catalogs and novel query techniques.

Main Results:

  • FGDB provides access to two gene sets derived from automated annotation, with ongoing manual curation.
  • The database facilitates retrieval of bioinformatics and functional classification data.
  • Gene sets were utilized for Affymetrix GeneChip design.

Conclusions:

  • FGDB serves as a valuable, accessible resource for researchers studying F. graminearum.
  • The database supports further investigation into the genomics and pathogenicity of this important fungal species.

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