Related Experiment Video
Updated: Aug 8, 2026

A Web Tool for Generating High Quality Machine-readable Biological Pathways
Published on: February 8, 2017
BioModels Database: a free, centralized database of curated, published, quantitative kinetic models of biochemical
Nicolas Le Novère1, Benjamin Bornstein, Alexander Broicher
1European Bioinformatics Institute EMBL, Wellcome-Trust Genome Campus, Hinxton, CB10 1SD, UK. lenov@ebi.ac.uk
Abstract:
BioModels Database (http://www.ebi.ac.uk/biomodels/), part of the international initiative BioModels.net, provides access to published, peer-reviewed, quantitative models of biochemical and cellular systems. Each model is carefully curated to verify that it corresponds to the reference publication and gives the proper numerical results. Curators also annotate the components of the models with terms from controlled vocabularies and links to other relevant data resources. This allows the users to search accurately for the models they need. The models can currently be retrieved in the SBML format, and import/export facilities are being developed to extend the spectrum of formats supported by the resource.
Related Concept Videos
Pharmacokinetic Models: Overview
There are three primary types of models: empirical, compartment, and physiological. Empirical models, with minimal assumptions,...
Mechanistic Models: Overview of Compartment Models
Mechanistic Models: Compartment Models in Individual and Population Analysis
Physiological Pharmacokinetic Models: Assumption with Protein Binding
Model Approaches for Pharmacokinetic Data: Distributed Parameter Models
The distributed parameter models are specifically designed to account for variations and differences in some drug classes. This model is particularly useful for assessing regional concentrations of anticancer or...
Pharmacokinetic Models: Comparison and Selection Criterion
Physiological models take a detailed approach by considering specific molecular processes. They can predict drug distribution, metabolism, and elimination changes, providing a comprehensive understanding of how drugs interact with the body.

