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Continuous peritoneal dialysis in children: a single-centre experience in a developing country
Narayan Prasad1, Sanjeev Gulati, Amit Gupta
1Department of Nephrology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.
Pediatric Nephrology (Berlin, Germany)
|December 31, 2005
Summary
Continuous peritoneal dialysis (CPD) is a viable treatment for children with end-stage renal failure (ESRF) in developing nations. This study shows CPD effectively bridges patients to kidney transplantation, offering a crucial therapeutic option.
Area of Science:
- Pediatric Nephrology
- Renal Replacement Therapy
Background:
- Continuous peritoneal dialysis (CPD) is the primary dialysis method for pediatric end-stage renal failure (ESRF).
- Limited data exists on CPD in children from developing countries.
Purpose of the Study:
- To evaluate the efficacy and outcomes of continuous ambulatory peritoneal dialysis (CAPD) in children with ESRF in India.
- To assess CAPD as a bridge to renal transplantation.
Main Methods:
- Retrospective study of 30 pediatric ESRF patients (mean age 13 years) on CAPD from 1994-2004.
- Analysis of peritonitis episodes, causative organisms, and patient outcomes including transplantation, mortality, and technique failure.
Main Results:
- The peritonitis rate was 0.58 episodes per patient-year, with E. coli being the most common pathogen.
- 23.3% of patients received a renal transplant, 36.6% were awaiting transplant, 26.6% died, and 6.7% experienced technique failure.
- The mean cumulative survival time for patients on CPD was 42 months.
Conclusions:
- Continuous peritoneal dialysis is a feasible and effective dialysis modality for children with ESRF in developing countries.
- CAPD serves as a successful bridge to renal transplantation, improving patient survival and quality of life.