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Updated: Aug 14, 2026

Rapid Genetic Analysis of Epithelial-Mesenchymal Signaling During Hair Regeneration
Published on: February 28, 2013
Plasticity of rodent and human hair follicle dermal cells: implications for cell therapy and tissue engineering
Gavin D Richardson1, Elisabeth C Arnott, Claire J Whitehouse
1School of Biological & Biomedical Sciences, University of Durham, Durham, NC, USA.
Abstract:
The dermal components of the hair follicle exhibit a number of stem cell properties, including regenerative potential, roles in wound healing and the ability to produce a functional dermis. Here we examine the stem cell phenomenon of plasticity, focusing on recent observations of in vitro plasticity of dermal papilla and sheath cells, including previously unpublished data of neuronal-like differentiation. We then briefly address the implications of the stem cell potential of hair follicle dermal cells for the field of tissue engineering.
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