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Quantitative pupillometry: normative data in healthy pediatric volunteers
Angel N Boev1, Kostas N Fountas, Ioannis Karampelas
1Department of Neurosurgery, The Medical Center of Central Georgia, Mercer University, School of Medicine, Macon, USA.
Insights
A new handheld pupillometer accurately measured pupil function in children. The device demonstrated reliable replication of pupil size and constriction/dilation velocities in pediatric participants.
Area of Science:
- Ophthalmology
- Pediatric Neurology
- Medical Device Technology
Background:
- Accurate assessment of pupil function is crucial for diagnosing neurological and ophthalmological conditions.
- Traditional pupillometry methods can be subjective and time-consuming.
- Quantitative, objective measurements are needed for improved clinical evaluation.
Purpose of the Study:
- To evaluate the prospective use of a novel handheld point-and-shoot pupillometer (NeurOptics) for quantitative pupil function assessment.
- To determine the reliability and reproducibility of measurements in a pediatric cohort.
Main Methods:
- Prospective study involving 90 pediatric participants (ages 1-18 years).
- Total of 100 measurements taken under ambient light conditions.
- Participants included healthy volunteers and patients without known intracranial or ophthalmological pathology.
Main Results:
- The handheld pupillometer reliably replicated quantitative pupil measurements.
- Mean resting pupil aperture: 4.11 mm; minimal diameter post-stimulation: 2.65 mm (36% change).
- Mean constriction velocity: 2.34 mm/second; mean dilation velocity: 2.2 mm/second.
Conclusions:
- The NeurOptics pupillometer offers a reliable method for quantitative pupil function assessment in children.
- Impressive pupil symmetry was observed across the entire pediatric cohort.
- This device has potential for objective and efficient clinical evaluation of pupil dynamics.
Object:
The authors describe the prospective use of a new hand-held point-and-shoot pupillometer (NeurOptics) to assess pupil function quantitatively.
Methods:
Repetitive measurements were made in 90 pediatric participants ranging in age from 1 to 18 years, providing a total of 100 measurements under ambient light conditions. The participants consisted of 45 patients without known intracranial or ophthalmological pathological conditions as well as 45 volunteers in the outpatient setting. Quantitative pupil measurements were reliably replicated in the study participants. The mean resting pupil aperture was 4.11 mm and the minimal diameter after stimulation was 2.65 mm, resulting in a 36% change in pupil size. The mean constriction velocity was 2.34 mm/second, with a mean dilation velocity of 2.2 mm/second.
Conclusion:
Pupil symmetry was impressive in the entire cohort.
