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Sister chromatid exchange frequency in breast cancer cases
S A Husain1, S Balasubramanian, R Bamezai
1Department of Human Biology and Human Genetics, Guru Nanak Dev University, Amritsar, Punjab, India.
Cancer Genetics and Cytogenetics
|July 15, 1992
Abstract:
Sister chromatid exchange (SCE) were studied in 22 patients with breast cancer (i.e., four stage II; 12 stage III, six stage IV) and 10 normal healthy females as age-matched controls. The data obtained in these cases followed a Poisson distribution. An apparent increase in the average rate of SCE/cell was observed with the advancing stage of breast cancer.