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Xanthogranulomatous appendicitis.

Yi-Fang Chuang1, Tsun-I Cheng, Thomas C Soong

  • 1Department of Psychiatry, National Taiwan University Hospital, Taipei, Taiwan.

Journal of the Formosan Medical Association = Taiwan Yi Zhi
|December 31, 2005
PubMed
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Xanthogranulomatous appendicitis is rare but can mimic cancer. Surgical resection offers a cure for this benign condition.

Area of Science:

  • Gastroenterology
  • Pathology
  • Surgical Oncology

Background:

  • Xanthogranulomatous inflammation is uncommon, typically affecting the kidney or gallbladder.
  • Reports of xanthogranulomatous inflammation in the appendix are rare.

Observation:

  • A 39-year-old male presented with fever, right lower quadrant pain, and a mass.
  • Imaging revealed ileocecal wall thickening and mesenteric involvement.
  • Biopsy indicated colitis, but symptoms persisted despite antibiotic treatment.

Findings:

  • Pathology confirmed xanthogranulomatous appendicitis after right hemicolectomy.
  • The condition mimicked locally advanced cecal cancer.
  • Xanthogranulomatous appendicitis has a benign clinical course.

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Implications:

  • This case highlights the importance of considering xanthogranulomatous appendicitis in the differential diagnosis of ileocecal masses.
  • Early surgical intervention can lead to a complete cure.
  • Accurate diagnosis is crucial to avoid unnecessary aggressive treatment for a benign entity.