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Lemierre's syndrome.

Ming-Yieh Peng1, Cheng-Kuo Fan, Feng-Yee Chang

  • 1Division of Infectious Diseases and Tropical Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.

Journal of the Formosan Medical Association = Taiwan Yi Zhi
|December 31, 2005
PubMed
Summary

Lemierre's syndrome, a severe condition involving internal jugular vein thrombus, can arise from throat infections. Early recognition and antibiotic treatment are crucial for recovery from this rare disease.

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Area of Science:

  • Infectious Diseases
  • Vascular Surgery
  • Otolaryngology

Background:

  • Lemierre's syndrome is a rare but serious complication of oropharyngeal infections.
  • It involves septic thrombophlebitis of the internal jugular vein with potential for metastatic emboli.

Observation:

  • A 20-year-old male presented with recurrent fever and painful neck swelling after tonsillitis.
  • Imaging revealed left internal jugular vein thrombosis and cavitary pulmonary infiltrates.

Findings:

  • Blood cultures identified Fusobacterium necrophorum, sensitive to metronidazole.
  • The patient recovered fully after 21 days of intravenous ceftriaxone and metronidazole.

Implications:

  • This case highlights the importance of considering Lemierre's syndrome in febrile patients with neck swelling.
  • Prompt diagnosis and appropriate antibiotic therapy are vital for managing this potentially life-threatening condition.

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