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A Competent Hepatocyte Model Examining Hepatitis B Virus Entry through Sodium Taurocholate Cotransporting Polypeptide as a Therapeutic Target
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A Competent Hepatocyte Model Examining Hepatitis B Virus Entry through Sodium Taurocholate Cotransporting Polypeptide as a Therapeutic Target

Published on: May 10, 2022

[Therapy of hepatitis B and hepatitis C coinfection in HIV patients]

M Vogel1, J K Rockstroh

  • 1Medizinische Universitätsklinik I, Bonn. martin.vogel@ukb.uni-bonn.de

MMW Fortschritte Der Medizin
|January 3, 2006
PubMed

Hepatitis coinfection represents a major risk for end stage liver disease in HIV-positive patients. For this reason, categorically every patient should be evaluated in respect to a specific treatment for hepatitis. The immunological benefit of HAART for hepatitis/HIV coinfected patients is not only a reduction of the risk for HIV disease, but also the reduction of the risk for liver associated diseases and outweighs the drawbacks of a potential hepatotoxicity of HAART. Thus, HAART should not be withheld from a patient because of hepatitis coinfection. When cirrhosis is present, semiannual prophylactic checkups are recommended to monitor the occurrence of hepatocellular carcinoma.

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