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Updated: Aug 13, 2026
Application of Acupotomy in a Knee Osteoarthritis Model in Rabbit
Published on: October 20, 2023
Does knee osteoarthritis alter the neuromuscular responses to a perturbation during single lower limb stance?
Kent E Irwin1, Jason D Wening, Tanvi Bhatt
1RUSH Oak Park Hospital, Department of Physical Therapy, Oak Park, IL 60304, USA. kirwin1@uic.edu
Purpose:
Evidence substantiating an association between knee osteoarthritis (OA) and altered joint protection responses is relevant to the management of knee OA. The purpose of this study was to detect neuromuscular response times of the vastus lateralis and biceps femoris muscles following a perturbation during single lower limb stance. We hypothesized that muscle response times are: (1) delayed in older adults with knee OA when compared to young and older adults (without diagnosed knee OA) and (2) dependent on the magnitude of load released.
Subjects:
Ten young adults, 10 older adults, and 7 older adults with symptomatic knee OA participated.
Methods:
While in single lower limb stance, the subjects flexed the knee into a range of 33 to 37 degrees while a posterior load of either 6 or 9 kg was applied at the proximal tibia. The load was released after the subjects held the required position for 1 full second. Muscle response times were measured by electromyography. Separate 3 (group) by 2 (load) mixed factorial analysis of variance procedures were performed for electromyography data from the vastus lateralis and biceps femoris.
Results:
There was no difference in vastus lateralis response times between older adults with knee OA and older adults or between older adults with knee OA and young adults. Older adults did have longer vastus lateralis response times than young adults. There was no difference in biceps femoris response times between older adults with knee OA and older adults; however, both groups had longer biceps femoris response times than young adults. Furthermore, there were no differences in either vastus lateralis or biceps femoris response times between 6 kg and 9 kg loads.
Conclusion:
Although knee OA did not alter muscle responses in our study, the type of functional weightbearing perturbation described could be safely used in the physical therapy clinic to help improve balance and stability while decreasing discomfort in older adults with symptomatic knee OA.
