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Updated: Aug 12, 2026
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Normothermic Ex Vivo Kidney Perfusion for the Preservation of Kidney Grafts prior to Transplantation
Published on: July 15, 2015
Expanded criteria donors for kidney transplantation
1Division of Transplantation, Department of Surgery, University of Michigan Health System, Scientific Registry of Transplant Recipients, Ann Arbor, 48109, USA. merionb@umich.edu
Transplantation Proceedings
|January 3, 2006
Summary
Kidney transplants from expanded criteria donors (ECD) are crucial due to organ shortages. Policy changes aim to improve outcomes for these vital kidney transplants, benefiting more recipients.
Area of Science:
- Nephrology
- Transplantation Medicine
- Public Health Policy
Background:
- Persistent shortage of deceased donor kidneys limits transplantation access.
- Increased utilization of expanded criteria donor (ECD) kidneys raises concerns about graft survival.
- National organ allocation policies have been modified to enhance kidney procurement and utilization.
Purpose of the Study:
- To review the effects of recent US policy changes regarding ECD kidney transplantation.
- To examine the impact of ECD kidney transplantation on mortality risk for waitlisted candidates.
- To identify areas for further research to optimize the use of ECD kidneys.
Main Methods:
- Review of recent studies on US organ allocation policy changes.
- Analysis of mortality risk associated with ECD kidney transplantation.
- Examination of graft outcomes for recipients of ECD kidneys.
Main Results:
- Policy modifications have aimed to increase kidney procurement and improve utilization.
- The impact of ECD kidney transplantation on waitlist mortality risk has been assessed.
- Graft outcomes for ECD kidneys require continued evaluation.
Conclusions:
- ECD kidney transplantation is essential for addressing donor organ scarcity.
- Ongoing research is needed to optimize the use and outcomes of ECD organs.
- Further studies on ECD organs and recipients are vital for maximizing resource utilization.
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