Related Experiment Videos
Vitamin E in the treatment of uveitis-associated macular edema
Robert B Nussenblatt1, Jonghyeon Kim, Darby J S Thompson
1Laboratory of Immunology, National Eye Institute, National Institutes of Health, Building 10, Rm. 10S219, 10 Center Drive, Bethesda, MD 20892, USA. drbob@nei.nih.gov
Purpose:
To investigate whether high-dose alpha-tocopherol (vitamin E) could reduce vision loss and retinal thickening associated with uveitis-associated cystoid macular edema.
Design:
A double-masked, randomized study.
Methods:
Uveitis patients with macular edema seen at the NIH were randomized and received either 1600 IU/day of vitamin E or placebo for 4 months. Visual acuity and retinal thickening were collected for the efficacy and the safety of the high dose of vitamin E.
Results:
Changes in visual acuity and retinal thickening.
Conclusions:
Four-month oral supplementation with 1600 IU/d of vitamin E had no apparent effect on uveitis-associated macular edema or visual acuity in this small study.
Related Concept Videos
Open Angle Glaucoma: Treatment
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment
Diabetic Retinopathy
Treatment for Pulmonary Arterial Hypertension: Endothelin Receptor Antagonists
ETs are synthesized through a complex sequence of enzymatic steps, primarily involving an enzyme referred to as endothelin-converting enzyme (ECE). Of...