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Effect of mixed mutans streptococci colonization on caries development.
M Seki1, Y Yamashita, Y Shibata
1Department of Oral Health Sciences, Dental Research Center, Nihon University School of Dentistry, Tokyo, Japan. seki-m@dent.nihon-u.ac.jp
Oral Microbiology and Immunology
|January 5, 2006
Summary
Mixed mutans streptococci colonization is a significant predictor of caries development in young children. This finding highlights the importance of monitoring specific bacterial profiles for early caries risk assessment in pediatric dentistry.
Area of Science:
- Pediatric Dentistry
- Microbiology
- Oral Health
Background:
- Dental caries remains a prevalent issue in preschool children.
- Understanding predictors of early childhood caries is crucial for effective prevention strategies.
Purpose of the Study:
- To assess the clinical significance of mixed mutans streptococci colonization in predicting caries development among preschool children.
- To identify key factors associated with caries incidence in primary dentition.
Main Methods:
- A longitudinal study involving 410 preschool children aged 3-4 years.
- Mutans streptococci (MS) colonization was assessed using plaque and saliva samples via a commercial strip method.
- Polymerase chain reaction (PCR) assays were employed for typing Streptococcus sobrinus and Streptococcus mutans (serotypes c, e, f).
Main Results:
- Univariate analysis identified 16 significant variables associated with caries development.
- Logistic regression revealed five key predictors: baseline caries experience, mixed MS colonization, high plaque MS score, frequent consumption of sweet drinks, and lack of fluoride toothpaste use.
- Mixed colonization of S. sobrinus and S. mutans, including S. mutans serotypes, emerged as a significant predictor.
Conclusions:
- Mixed mutans streptococci colonization represents a novel and clinically relevant measure for predicting caries in primary dentition.
- Early identification of mixed MS colonization can aid in targeted caries prevention efforts in young children.