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Updated: Aug 13, 2026

Development of a Neonatal Piglet Acute Lung Injury Model Recreating the Early Environment of Preterm Infant Lungs
Published on: October 31, 2025
Current concepts on the pulmonary surfactant in infants
S Parmigiani1, E Solari, G Bevilacqua
1Department of Gynecologic, Obstetric and Neonatologic Sciences, Section of Child Health and Neonatology, University of Parma, Parma, Italy. sparmigiani@ao.pr.it
Abstract:
Surfactant has been a main topic of neonatology in the last 20 years. Many studies have been conducted since the discovery of its role in the pathogenesis of respiratory distress syndrome and the knowledge on its composition and metabolism has become complex. In this article we review the current concepts of its metabolism, ways of acting, properties of its proteins and activities other than the ability of reducing surface tension within the lung as a basis to understand the development of disease in case of its deficiency.
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