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T cell targeted immunotherapy for autoimmune disease

Erica Lee1, Animesh A Sinha

  • 1Department of Dermatology, Weill Medical College of Cornell University, New York, NY, USA.

Autoimmunity
|January 5, 2006
PubMed

Much emphasis has been placed on the so-called "biologics" in the treatment of immune disorders within the last few years. Here we discuss the expanding horizon of potential strategies for immunotherapies targeting T lymphocytes as key effectors and regulators of autoimmunity. We review emerging reagents in a variety of animal models and human disorders that may offer new therapeutic options in current or modified iterations.

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