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Published on: February 29, 2020
Bacterial meningitis among children with cochlear implants beyond 24 months after implantation
Krista R Biernath1, Jennita Reefhuis, Cynthia G Whitney
1National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA. kbiernath@cdc.gov
Insights
Children with cochlear implants, especially those with positioners, face a continued high risk of bacterial meningitis for over two years post-implantation. Ongoing vigilance and vaccination are crucial for these pediatric patients.
Area of Science:
- Pediatric Otolaryngology
- Infectious Disease Epidemiology
- Biomedical Engineering
Background:
- Cochlear implants are used by over 11,000 US children with severe-to-profound hearing loss.
- A prior study found pneumococcal meningitis incidence >30 times higher in pediatric cochlear implant recipients.
- Children with cochlear implants with positioners had a higher risk of bacterial meningitis for up to 24 months post-implantation.
Purpose of the Study:
- To determine if the elevated risk of bacterial meningitis in pediatric cochlear implant recipients extends beyond 24 months.
- To update incidence rates of bacterial meningitis in this vulnerable population.
Main Methods:
- The study cohort included 4,265 children (<6 years at implantation) who received cochlear implants between 1997 and 2002.
- Updated incidence rates were calculated, focusing on time since implantation.
- New meningitis cases were identified and analyzed.
Main Results:
- Twelve new meningitis episodes were identified in 12 children; 11 had implants with positioners, and 2 children died.
- Six meningitis episodes occurred more than 24 months after implantation.
- The incidence of bacterial meningitis >=24 months post-implantation was 450 cases/100,000 person-years for children with positioners, versus zero for those without.
Conclusions:
- The increased risk of bacterial meningitis persists beyond 24 months post-implantation, particularly for children with positioners.
- Healthcare providers and parents must maintain vigilance for bacterial infections in children with cochlear implants.
- Current vaccination recommendations apply to all children with cochlear implants, regardless of device type.
Background:
More than 11000 children in the United States with severe-to-profound hearing loss have cochlear implants. A 2002 investigation involving pediatric cochlear implant recipients identified meningitis episodes from January 1, 1997, through September 15, 2002. The incidence of pneumococcal meningitis in the cohort was 138.2 cases per 100000 person-years, >30 times higher than that for children in the general US population. Children with implants with positioners were at higher risk than children with other implant models. This higher risk of bacterial meningitis continued for up to 24 months after implantation.
Objective:
To evaluate additional reported cases to determine whether the increased rate of bacterial meningitis among children with cochlear implants extended beyond 24 months after implantation.
Methods:
Our study population consisted of the cohort of children identified through the 2002 investigation; it included 4265 children who received cochlear implants in the United States between January 1, 1997, and August 6, 2002, and who were <6 years of age at the time of implantation. We calculated updated incidence rates and incidence according to time since implantation.
Results:
We identified 12 new episodes of meningitis for 12 children. Eleven of the children had implants with positioners; 2 children died. Six episodes occurred >24 months after implantation. When cases identified in the 2002 and 2004 investigations were combined, the incidence rate of > or =24-months postimplantation bacterial meningitis among children with positioners was 450 cases per 100000 person-years, compared with no cases among children without positioners.
Conclusions:
Our updated findings support continued monitoring and prompt treatment of bacterial infections by health care providers and parents of children with cochlear implants. This vigilance remains important beyond 2 years after implantation, particularly among children with positioners. The vaccination recommendations for all children with implants, with and without positioners, and all potential recipients of implants continue to apply.
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