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Related Experiment Videos

"Cherry-red spot" or "perifoveal white patch"?

Luis H Ospina1, Christopher J Lyons, Andrew Q McCormick

  • 1Department of Ophthalmology, University of British Columbia, BC Children's Hospital, Vancouver, B.C.

Canadian Journal of Ophthalmology. Journal Canadien D'Ophtalmologie
|January 5, 2006
PubMed
Summary
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The "cherry red spot" in metabolic disease may appear as a perifoveal white patch, not always red. This finding in fundus photography offers a more accurate description for diverse racial backgrounds.

Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Metabolic Diseases

Background:

  • The normal fovea appears red in Caucasians.
  • Metabolic product accumulation can cause retinal pallor and alter surrounding retinal color.
  • The term "cherry red spot" is commonly used but may not accurately describe all presentations.

Purpose of the Study:

  • To present fundus photographs of patients with metabolic disease showing foveal changes.
  • To evaluate the accuracy of the term "cherry red spot" across different races.
  • To propose a more accurate descriptive term for this clinical finding.

Main Methods:

  • Photo-essay format presenting fundus photographs.
  • Case series of 3 patients from different racial backgrounds with metabolic disease.

Related Experiment Videos

  • Discussion of pathological entities, histology, and anatomy.

    • Main Results:

    • Fundus photographs revealed a contrasting foveal appearance in patients with metabolic disease.
    • The characteristic finding was not consistently red across different races.
    • The term "perifoveal white patch" is suggested as a more accurate descriptor.

    Conclusions:

    • The appearance of the fovea in metabolic disease can vary and is not always red.
    • "Perifoveal white patch" may be a more precise term than "cherry red spot" for this fundus finding.
    • Understanding the pathological basis is crucial for interpreting this sign.