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Related Concept Videos

Biological Effects of Radiation02:59

Biological Effects of Radiation

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All radioactive nuclides emit high-energy particles or electromagnetic waves. When this radiation encounters living cells, it can cause heating, break chemical bonds, or ionize molecules. The most serious biological damage results when these radioactive emissions fragment or ionize molecules. For example, α and β particles emitted from nuclear decay reactions possess much higher energies than ordinary chemical bond energies. When these particles strike and penetrate matter, they...
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Radiation: Applications01:17

Radiation: Applications

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The average temperature of Earth is the subject of much current discussion. Earth is in radiative contact with both the Sun and dark space; it receives almost all its energy from the radiation of the Sun and reflects some of it into outer space. Dark space is very cold, about 3 K, so Earth radiates energy into it. For instance, heat transfer occurs from soil and grasses, the rate of which can be so rapid that frost can occur on clear summer evenings, even in warm latitudes.
The average...
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Absorption of Radiation01:05

Absorption of Radiation

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The rate of heat transfer by emitted radiation is described by the Stefan-Boltzmann law of radiation:
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Radiation Pressure: Problem Solving01:09

Radiation Pressure: Problem Solving

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The radiation pressure applied by an electromagnetic wave on a perfectly absorbing surface equals the energy density of the wave. The wave's momentum also gets transferred to the surface when an electromagnetic wave is entirely absorbed by it. The rate at which momentum is transmitted to an absorbing surface perpendicular to the propagation direction equals the force on the surface.
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Generating Electromagnetic Radiations01:10

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The German physicist Heinrich Hertz (1857–1894) was the first to generate and detect certain types of electromagnetic waves in the laboratory. Starting in 1887, he performed a series of experiments that confirmed the existence of electromagnetic waves and verified that they travel at the speed of light. Hertz used an alternating-current RLC (resistor-inductor-capacitor) circuit that resonated at a known frequency and connected it to a loop of wire. High voltages induced across the gap in...
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Gene Therapy00:59

Gene Therapy

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Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be...
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Related Experiment Video

Updated: Feb 7, 2026

Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform
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Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform

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Radiation therapy in the elderly.

Loren K Mell1, Arno J Mundt

  • 1Department of Radiation and Cellular Oncology, University of Chicago, Chicago, Illinois 60637, USA.

Cancer Journal (Sudbury, Mass.)
|January 6, 2006
PubMed
Summary

This review covers radiation oncology for older cancer patients, focusing on efficacy and toxicity of radiation therapy (RT) in this demographic. It also examines specialized techniques relevant to elderly cancer care.

Area of Science:

  • Geriatric Oncology
  • Radiation Oncology
  • Cancer Treatment

Background:

  • Aging population presents unique challenges in cancer care.
  • Older patients often have comorbidities affecting treatment tolerance.
  • Radiation therapy (RT) is a cornerstone of cancer treatment, but its application in the elderly requires careful consideration.

Purpose of the Study:

  • To review the specific aspects of radiation oncology for aging individuals with cancer.
  • To emphasize preclinical and clinical data on the efficacy and toxicity of RT in the elderly cancer population.
  • To discuss specialized RT techniques pertinent to older patients.

Main Methods:

  • Literature review of preclinical and clinical studies.
  • Analysis of radiation therapy efficacy and toxicity data in older adults.

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  • Synthesis of information on specialized RT techniques for the elderly.
  • Main Results:

    • Radiation therapy efficacy and toxicity profiles in older patients are distinct.
    • Specific RT techniques can optimize treatment delivery and reduce side effects in the elderly.
    • Further research is needed to fully elucidate optimal RT strategies for geriatric cancer patients.

    Conclusions:

    • Radiation oncology for older cancer patients requires tailored approaches.
    • Understanding age-related factors is crucial for effective and safe RT delivery.
    • Specialized techniques and ongoing research are vital for improving outcomes in this population.