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Diffusion tensor imaging of the spinal cord.

Stephan E Maier1, Hatsuho Mamata

  • 1Radiology (MRI), Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA. stephan@bwh.harvard.edu

Annals of the New York Academy of Sciences
|January 6, 2006
PubMed
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Magnetic resonance diffusion tensor imaging reveals detailed spinal cord fiber architecture. This study outlines normal diffusion tensor imaging findings in the spinal cord across various age groups.

Area of Science:

  • Neuroscience
  • Medical Imaging

Background:

  • The spinal cord connects the brain to the periphery, featuring complex fiber architecture and gray matter structures.
  • Understanding spinal cord anatomy is crucial for neurological function and diagnosis.

Purpose of the Study:

  • To summarize normal findings from magnetic resonance diffusion tensor imaging (DTI) of the spinal cord.
  • To detail apparent diffusion coefficient (ADC), diffusion anisotropy, and eigenvector directions in the spinal cord.

Main Methods:

  • Utilized line scan diffusion imaging (LSDI) to acquire sagittal and axial diffusion-weighted images.
  • Examined DTI parameters in adults, children, infants, and a spinal cord specimen.

Main Results:

  • Presented normal values for ADC, diffusion anisotropy, and diffusion eigenvector directions.

Related Experiment Videos

  • Demonstrated the capability of DTI to visualize intricate spinal cord fiber architecture.

    • Conclusions:

    • DTI provides detailed insights into the normal microstructural organization of the spinal cord.
    • Established normative DTI data is essential for interpreting spinal cord pathologies.