Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Applications of diffusion tensor MR imaging in multiple sclerosis.

Yulin Ge1, Meng Law, Robert I Grossman

  • 1Department of Radiology, New York University Medical Center, 530 First Avenue, Basement HCC, New York, NY 10016, USA.

Annals of the New York Academy of Sciences
|January 6, 2006
PubMed
Summary

Diffusion tensor imaging (DTI) offers a sensitive method for studying white matter changes in multiple sclerosis (MS). This review explores DTI and fiber tractography

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Impact of multiple sclerosis disease-modifying therapies on chronic lesion tissue expansion.

Multiple sclerosis (Houndmills, Basingstoke, England)·2026
Same author

Implementation of Electronic Clinical Decision Support for Radiology Referrals: The Role of Governance, Clinician Engagement and Education.

Emergency medicine Australasia : EMA·2026
Same author

Sex-related structural alterations across common epilepsies: a worldwide ENIGMA study.

bioRxiv : the preprint server for biology·2026
Same author

Population-based Brain Templates for Ultra-Low-Field MRI.

Scientific data·2026
Same author

Short T1 Fraction as a Marker of Myelin Content: Evidence from Postmortem MRI and Histology.

bioRxiv : the preprint server for biology·2026
Same author

T<sub>1</sub> Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions.

Annals of clinical and translational neurology·2026

Area of Science:

  • Neuroimaging
  • Neurology
  • Biomedical Engineering

Background:

  • Multiple sclerosis (MS) is a central nervous system inflammatory demyelinating disease causing significant disability in young adults.
  • Magnetic resonance imaging (MRI) is crucial for MS diagnosis, natural history assessment, and treatment monitoring.
  • Advanced MRI techniques are vital for detecting subtle white matter pathology in MS.

Purpose of the Study:

  • To review the current applications of Diffusion Tensor Imaging (DTI) in multiple sclerosis research.
  • To explore the potential of DTI and fiber tractography for assessing white matter integrity in MS.
  • To outline future directions for DTI in the study of MS disease processes.

Main Methods:

  • Review of current literature on Diffusion Tensor Imaging (DTI) and fiber tractography in multiple sclerosis (MS).

Related Experiment Videos

  • Focus on DTI's ability to quantify water diffusion and infer microstructural damage in vivo.
  • Examination of advanced quantitative MRI techniques beyond conventional methods.

    • Main Results:

    • DTI provides sensitive and reliable in vivo assessment of white matter pathological changes in MS.
    • Fiber tractography visualizes white matter tracts, offering insights into microstructural damage.
    • Advanced DTI techniques show promise for greater pathological specificity and sensitivity in MS studies.

    Conclusions:

    • Diffusion Tensor Imaging (DTI) is a key advanced MRI technique for studying MS.
    • DTI and fiber tractography offer unique insights into white matter integrity and disease progression in MS.
    • Continued research into DTI holds significant potential for understanding and managing MS.