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Updated: Aug 13, 2026

Automated Gait Analysis to Assess Functional Recovery in Rodents with Peripheral Nerve or Spinal Cord Contusion Injury
Published on: October 6, 2020
Closed fractures complicated by peripheral nerve injury
L Randall Mohler1, Douglas P Hanel
1Section of Hand and Microvascular Surgery, Department of Orthopaaedics and Sports Medicine, University of Washington, Seattle, WA 98104-2499, USA.
Peripheral nerve injuries associated with closed fractures often heal favorably with conservative treatment, including splinting and exercise. Surgical exploration is recommended only if recovery signs are absent after six months, guiding further nerve repair strategies.
Area of Science:
- Orthopedic Surgery
- Neurology
- Traumatology
Background:
- Closed fractures can involve peripheral nerve injuries, complicating treatment decisions due to limited clinical data.
- Most associated nerve injuries are local and without division, generally having a good prognosis.
Purpose of the Study:
- To outline optimal management strategies for peripheral nerve injuries in the context of closed fractures.
- To establish criteria for surgical intervention and guide intraoperative decision-making.
Main Methods:
- Review of clinical presentation and outcomes for peripheral nerve injuries secondary to closed fractures.
- Emphasis on conservative management (splinting, exercise) in the acute phase.
- Guidelines for electrodiagnostic testing and surgical exploration at six months if recovery is lacking.
Main Results:
- Immediate surgery is typically not warranted for closed fractures with nerve injury.
- Conservative management with splinting and exercise is the preferred initial approach.
- Surgical exploration at six months is indicated for non-recovering nerve injuries, with intraoperative nerve action potential measurements guiding repair techniques.
Conclusions:
- Peripheral nerve injuries from closed fractures usually benefit from initial non-operative management.
- Delayed surgical exploration with objective nerve testing is crucial for optimizing functional recovery in persistent cases.
- Intraoperative nerve action potential measurements are key to selecting the most effective surgical repair method.
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