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House dust mite sensitivity is a factor in chronic urticaria
P A Mahesh1, P A Kushalappa, Amrutha D Holla
1Department of Pulmonology, JSS Medical College, Mysore, India. maheshapa@sancharnet.in
Indian Journal of Dermatology, Venereology and Leprology
|January 6, 2006
Summary
House dust mite sensitivity is linked to chronic urticaria. A significant percentage of patients with chronic urticaria showed skin sensitivity to house dust mites, suggesting a potential connection.
Area of Science:
- Allergy and Immunology
- Dermatology
Background:
- Chronic urticaria presents a diagnostic challenge for clinicians.
- Existing research suggests a potential link between house dust mite sensitivity and chronic urticaria.
Purpose of the Study:
- To explore the association between house dust mite sensitivity and chronic urticaria.
- To determine if house dust mite allergy is a contributing factor in chronic urticaria development.
Main Methods:
- A case-control study involving three groups: chronic urticaria patients (73), chronic urticaria with other allergies (49), and healthy controls (25).
- Skin prick testing was performed using Dermatophagoides pteronyssinus (DP) and Dermatophagoides farinae (DF) antigens.
Main Results:
- 64% of chronic urticaria patients (78/122) exhibited skin sensitivity to house dust mites.
- Sensitivity was higher in those with co-existing allergies (79%) compared to chronic urticaria alone (53%).
- 28% of the healthy control group showed positive skin reactions to house dust mites.
Conclusions:
- The study indicates a probable association between house dust mite sensitivity and chronic urticaria.
- House dust mite allergy may play a role in the pathogenesis of chronic urticaria.
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