Visualization of neointima formation by optical coherence tomography
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Updated: Aug 13, 2026

Imaging In-Stent Restenosis: An Inexpensive, Reliable, and Rapid Preclinical Model
Published on: September 14, 2009
Teruyoshi Kume1, Takashi Akasaka, Takahiro Kawamoto
1Department of Cardiology, Kawasaki Medical School, Okayama, Japan.
Abstract:
Optical coherence tomography (OCT) has recently been proposed as a high-resolution imaging method. Our male patient, who had been treated with a coronary stent, died due to acute leukemia. Coronary artery images using intravascular ultrasound (IVUS) and OCT were obtained postmortem. We also compared the image of neointima formation after stent implantation evaluated by histopathological examination with that evaluated by IVUS and OCT. OCT visualized well-apposed stent struts and neointima formation, which could not be visualized completely by IVUS. OCT may be useful for monitoring structural changes after stent implantation.

