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Updated: Aug 13, 2026

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Modeling Primary Bone Tumors and Bone Metastasis with Solid Tumor Graft Implantation into Bone
Published on: September 9, 2020
Case reports: Osteosarcoma without radiographic evidence of tumor
Brandon A Ramo1, Michael Kyriakos, Douglas J McDonald
1Department of Orthopaedic Surgery, Washington University School of Medicine, St. Louis, MO 63110, USA.
Clinical Orthopaedics and Related Research
|January 6, 2006
Abstract:
There have been cases of osteosarcoma in which conventional radiographs showed only minimal abnormalities. However, the absence of any evidence of tumor has not been reported. We report a unique case of osteosarcoma in a patient who originally presented with a fracture incurred after minimal trauma. The patient had no radiographic evidence of the tumor even after retrospective analysis.

