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Published on: February 10, 2023
Venous thromboembolic events in pediatric trauma patients: is prophylaxis necessary?
Michelle C Azu1, Jane E McCormack, Richard J Scriven
1Department of Surgery, Stony Brook University Hospital, Stony Brook, New York 11974, USA.
Insights
Pediatric trauma patients under 13 years old have a negligible risk of venous thromboembolic events (VTE). Prophylaxis for VTE is not necessary in this young trauma population, simplifying care protocols.
Area of Science:
- Trauma Care
- Pediatric Critical Care
- Vascular Medicine
Background:
- Venous thromboembolic events (VTE) are significant complications in adult trauma patients.
- Current VTE prophylaxis strategies are established for adults but not well-defined for pediatric trauma.
- The necessity of VTE prophylaxis in pediatric trauma patients remains an open question.
Purpose of the Study:
- To evaluate the incidence of VTE in pediatric trauma patients.
- To determine if VTE prophylaxis is required in the pediatric trauma population.
- To compare VTE risk across different age groups within a trauma setting.
Main Methods:
- Retrospective analysis of a Level I trauma center registry (1994-2003).
- Patients categorized into three age groups: <13 years (Group I), 13-17 years (Group II), and >17 years (Group III).
- Group I received no VTE prophylaxis; Group III received standard prophylaxis; Group II prophylaxis was surgeon-dependent. Injury Severity Score (ISS) was recorded.
Main Results:
- A total of 13,880 patients were analyzed.
- No VTE occurred in the pediatric group (<13 years).
- Two VTE cases in adolescents (13-17 years) occurred in patients with ISS >24 and contraindications to prophylaxis; 59 VTEs occurred in adults (>17 years).
Conclusions:
- Clinically significant thromboembolic events are negligible in trauma patients under 13.
- VTE prophylaxis is not indicated for pediatric patients sustaining traumatic injuries.
- This finding supports a targeted approach to VTE prevention in pediatric trauma.
Background:
Venous thromboembolic events (VTE), such as deep vein thrombosis and pulmonary embolism, are major morbidities in adult trauma patients. Invasive and noninvasive prophylactic therapies are used to prevent VTE in trauma patients. The risk of VTE in pediatric patients is not well known. Is VTE prophylaxis necessary in the pediatric trauma population?
Methods:
This is a retrospective study from the trauma registry of a Level I trauma center from January 1, 1994, through December 31, 2003. Three separate age groups were reviewed: Group I, age less than 13 years; group II, age 13 to 17 years; and group III, age greater than 17 years. Group I did not receive any VTE prophylaxis. All patients in group III received invasive and noninvasive prophylaxis if not contraindicated. In group II, VTE prophylaxis was administered at the preference of the attending surgeon. All patients were assigned an Injury Severity Score at discharge.
Results:
A total of 13,880 patients were identified. Groups I, II, and III had 1,192; 1,021; and 10,568 patients, respectively. In group I, no patient developed a VTE. Two patients in group II developed VTE. Both had an Injury Severity Score of >24 and both had contraindication to invasive prophylaxis. In group III, 59 patients developed VTE.
Conclusion:
The risk of clinically significant thromboembolic event in trauma patients under age 13 is negligible. Therefore, VTE prophylaxis is unnecessary in pediatric patients with traumatic injury.
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