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Updated: Jul 22, 2026

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Published on: June 2, 2014
Prognostic factors, disability, and functional status among patients in a headache specialty practice
R R Coeytaux1, E L H Spierings
1University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA.
Abstract:
The objective of this study was to identify prognostic factors and assess functional status over time among patients in a headache specialty practice. Study questionnaires were mailed to 599 patients who previously presented to a headache specialty practice. Outcome measures included headache frequency, the Headache Impact Test (HIT) and the SF-36 Health Survey. Completed surveys were received from 333 respondents (56%). Thirty-five respondents (11%) had HIT scores in the 'little or no impact' range at follow-up and 191 (57%) had HIT scores in the 'severe impact' range. A diagnosis of migraine at baseline was an independent predictor of elevated HIT scores at follow-up, but gender, age, age at headache onset, daily headache at baseline, and time to follow-up did not predict poor prognosis. A subset of headache patients continue to experience marked disability and impaired functional status, months to years after presenting for headache specialty care. A diagnosis of migraine at the time of presentation may predict prognosis, but additional cohort studies with careful attention to baseline variables are needed to help identify other prognostic factors.

