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Myelomatous pleural effusion.

A Gogia¹, P K Agarwal, S Jain

¹Department of Medicine, Department of Nuclear Medicine, Sir Ganga Ram Hospital, Rajinder Nagar, New Delhi.

The Journal of the Association of Physicians of India

|January 10, 2006

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Multiple myeloma rarely causes pleural effusions, but this case highlights a myelomatous effusion diagnosed via pleural fluid cytology. Despite treatment, the patient

Area of Science:

Hematology
Oncology
Pulmonology

Background:

Multiple myeloma, a plasma cell malignancy, infrequently presents with pleural effusions.
Myelomatous pleural effusion, a rare manifestation, poses diagnostic and therapeutic challenges.

Observation:

A 66-year-old male with multiple myeloma developed a right-sided pleural effusion.
Diagnosis was confirmed through repeated cytopathological examination of pleural fluid.
The patient's condition deteriorated despite one cycle of cyclophosphamide and methylprednisolone.

Findings:

This case represents a rare instance of myelomatous pleural effusion in multiple myeloma.
Cytopathological analysis of pleural fluid is crucial for diagnosing such effusions.
The patient experienced a poor prognosis despite initial treatment.

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Implications:

Highlights the importance of considering myelomatous effusion in multiple myeloma patients with pleural effusions.
Underscores the diagnostic utility of pleural fluid cytology.
Suggests a need for further research into effective treatment strategies for this rare presentation.