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Updated: Aug 11, 2026

Using Chronic Social Stress to Model Postpartum Depression in Lactating Rodents
Published on: June 10, 2013
Post-partum depression and infant growth in a South African peri-urban settlement
M Tomlinson1, P J Cooper, A Stein
1Child Guidance Clinic, University of Cape Town, South Africa. mtomlins@protem.uct.ac.za
Aim:
To examine the association between maternal post-natal depression and infant growth.
Background:
Infant growth has recently been shown, in two studies from South Asia, to be adversely affected by maternal depression in the early post-partum period. It is uncertain whether a similar association obtains in developing countries outside Asia.
Method:
A sample of 147 mother-infant dyads was recruited from a peri-urban settlement outside Cape Town and seen at 2 and 18 months post partum.
Results:
No clear effect of post-partum depression on infant growth was found. Although maternal depression at 2 months was found to be associated with lower infant weight at 18 months, when birthweight was considered this effect disappeared.
Conclusions:
Possible explanations for the non-replication of the South Asian findings are considered.
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