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Updated: Jul 30, 2026

International Expert Consensus and Recommendations for Neonatal Pneumothorax Ultrasound Diagnosis and Ultrasound-guided Thoracentesis Procedure
Published on: March 12, 2020
Routine neonatal postextubation chest physiotherapy: a randomized controlled trial
C E Bagley1, P H Gray, D I Tudehope
1Department of Physiotherapy, University of Queensland, South Brisbane, Queensland, Australia. 21phymh@mater.org.au
Insights
Routine neonatal chest physiotherapy after extubation does not reduce postextubation collapse. This randomized controlled trial found no significant difference in adverse outcomes for infants receiving physiotherapy compared to standard care.
Area of Science:
- Neonatal care
- Pediatric respiratory medicine
- Clinical trials
Background:
- Postextubation collapse is a common complication in neonates requiring mechanical ventilation.
- Chest physiotherapy is sometimes used to prevent or treat respiratory complications in infants.
Purpose of the Study:
- To evaluate the effectiveness of a neonatal postextubation chest physiotherapy program.
- To determine if physiotherapy reduces postextubation collapse and adverse outcomes in mechanically ventilated infants.
Main Methods:
- A randomized controlled trial involving 177 neonates was conducted.
- Infants were assigned to either a physiotherapy group (chest percussion and suctioning) or a control group (suctioning only).
- Postextubation collapse was assessed via chest X-ray by a blinded radiologist.
Main Results:
- No statistically significant difference in postextubation collapse rates between the physiotherapy group (17.2%) and the control group (19.8%) was observed (P = 0.85).
- There were no significant differences in apnea, bradycardia, need for oxygen, or re-intubation rates between the groups.
- The trial was stopped early due to an interim analysis.
Conclusions:
- Routine neonatal postextubation chest physiotherapy is not indicated for all infants.
- The study found no evidence that chest physiotherapy is associated with adverse outcomes in this population.
Objective:
To test the effects of a neonatal postextubation programme on the incidence of postextubation collapse and adverse outcomes.
Methods:
A randomized controlled trial was carried out at the Mater Mothers' Hospital, Brisbane. Mechanically ventilated infants were randomized into one of two groups, physiotherapy group--which involved a regimen of chest wall percussion and oropharyngeal suctioning and control group - which involved suctioning without the percussion unless indicated. Chest X-rays were taken at 6 h and at 24 h postextubation. The primary outcome measure was postextubation collapse as determined by a paediatric radiologist blinded to the group allocation.
Results:
One hundred and seventy-seven neonates were enrolled in the trial between 1997 and 1999. After an interim analysis, the trial was stopped early. No statistically significant difference was shown in the rate of postextubation collapse (15 of 87 (17.2%) physiotherapy group and 17 of 86 (19.8%) control group (P = 0.85)). No differences were shown between the groups in the number of apnoeic or bradycardic events, duration of requirement for supplemental oxygen or the need for re-intubation within 24 h postextubation.
Conclusion:
The results of this trial suggest that a routine neonatal postextubation chest physiotherapy programme for all infants is not indicated. There was no evidence that chest physiotherapy is associated with any adverse outcomes.
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