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Acute poisoning in children
Muhammad Haroon Hamid1, Tayyaba Butt, Ghulam Raza Baloch
1Department of Paediatric Medicine, The Children's Hospital and the Institute of Child Health, Lahore, Pakistan. haroonr5@yahoo.com
Insights
Acute poisoning in children, primarily caused by pharmaceuticals and petroleum products, significantly impacts hospital admissions and outcomes. Increased awareness and education on household substance toxicity are crucial for prevention.
Area of Science:
- Pediatric Emergency Medicine
- Toxicology
- Public Health
Background:
- Acute poisoning is a significant cause of pediatric morbidity and mortality.
- Understanding the epidemiology of childhood poisoning is essential for targeted prevention strategies.
Purpose of the Study:
- To determine the frequency, etiology, clinical presentation, and outcomes of acute poisoning in children presenting to a tertiary care hospital.
- To identify common poisoning agents and risk factors in the pediatric population.
Main Methods:
- A descriptive, observational study was conducted over five years (September 1998 to August 2003).
- Retrospective analysis of 346 cases of acute poisoning in children (1 month to 15 years) admitted to the Emergency Department.
- Data collected included demographics, season, type of agent, route of exposure, clinical features, and outcomes.
Main Results:
- Acute poisoning accounted for 0.93% of all Emergency Department admissions.
- Pharmaceutical products (51%) and petroleum products (23%) were the leading causes, with anti-diarrheal drugs and kerosene oil being most frequent.
- Gastrointestinal involvement was common (40%), with an 11% mortality rate and 6% residual damage.
Conclusions:
- Acute poisoning poses a substantial burden on pediatric healthcare, leading to significant morbidity and mortality.
- Public awareness and education regarding the toxicity of common drugs and household substances are vital for reducing childhood poisoning incidents.
Objective:
To determine the frequency, etiology, clinical presentation and outcome of acute poisoning in children presenting to a tertiary care hospital.
Design:
Descriptive and observational study.
Place And Duration Of Study:
Emergency Department of the Children's Hospital and the Institute of Child Health, Lahore. Over five years from September 1998 to August 2003.
Material And Methods:
All cases of suspected or confirmed acute poisoning in children (1 month to 15 years) were retrospectively analyzed by retrieving data from hospital records and from patients files where possible. Variables like demographic data, season of presentation, type of agent, route of exposure and outcome were studied for all cases. Detailed files were available for 90 patients in whom place of exposure, risk factors and clinical features were also studied.
Results:
Three hundred and forty-six cases of acute poisoning were registered during the study period, which constitute 0.93% of all ER admission. Most (59%) were less than 2 years of age with median age of 18 months (SD+ 32.6). Majority (80%) belonged to urban areas and presented during summer and monsoon season (57%). Pharmaceutical products were the leading cause (51%) followed by petroleum products (23%), chemicals (8.4%), household substances (7.6%) and unidentifiable agents in 10% cases. Anti-diarrhoeal drugs and kerosene oil were the two most frequent agents involved and ingestion remained the primary route of exposure. Gastrointestinal system was primarily involved in 40% patients. Eighty percent patients were discharged, 6% with residual damage while 11% patients died of poisoning or its complications.
Conclusion:
Acute poisoning carries a significant impact as regards morbidity and mortality. Awareness and education about the potential toxicity of commonly used drugs and household substances may help in reducing the burden of acute poisoning in children.
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