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Remote controlled magnetically guided pulmonary vein isolation in canines
Scott Greenberg1, Walter Blume, Mitchell Faddis
1Washington University School of Medicine, St. Louis, Missouri, USA.
Heart Rhythm
|January 10, 2006
Summary
This study shows that a new remote-controlled magnetic catheter system is safe and effective for pulmonary vein isolation in canines, potentially improving atrial fibrillation ablation. This technology may reduce risks for patients and operators.
Area of Science:
- Cardiovascular Interventions
- Medical Device Technology
Background:
- Atrial fibrillation (AF) ablation is challenging, with significant risks and technical difficulties.
- A novel magnetically guided catheter system offers potential solutions.
- The study utilized a 3D computed tomogram (CT) for precise navigation.
Purpose of the Study:
- To evaluate the feasibility of pulmonary vein isolation using a novel, remote-controlled, magnetically guided catheter.
- To assess the safety and efficacy of this new technology in a preclinical model.
Main Methods:
- Seven healthy male canines underwent CT scans for anatomical reference.
- A 7-Fr irrigated magnetic catheter was guided transseptally to the left atrium.
- Radiofrequency energy was delivered for superior pulmonary vein isolation, guided by CT and magnetic vectors.
Main Results:
- Successful isolation of all 14 pulmonary veins was achieved.
- No stenosis was observed at 80-100 days post-procedure, indicating safety.
Conclusions:
- Remote-controlled catheter ablation using magnetic guidance is safe and effective for pulmonary vein isolation.
- This technology has the potential to facilitate curative AF ablation in humans.
- It may also reduce operator risks, including radiation exposure and procedural duration.