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Updated: Sep 16, 2026

OP-IVM: Combining In vitro Maturation after Oocyte Retrieval with Gynecological Surgery
Published on: May 9, 2021
Simultaneous induction of multiple follicular development with gonadotrophins and steroid replacement for in-vitro
A Pellicer1, M J De los Santos, J Remohí
1Department of Paediatrics, Valencia University School of Medicine, Spain.
Abstract:
Simultaneous administration of follicle stimulating hormone, oestradiol valerate and progesterone was employed in a patient with a possible enzymatic deficiency involving low production of oestradiol. The patient became pregnant after in-vitro fertilization. This case demonstrates that this treatment is useful in women with low oestradiol production and subsequent inadequate endometrial development; it also illustrates the role of oestradiol in follicular development and questions the importance of serum oestradiol measurements in the monitoring of ovulation induction.
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