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Human Primary Trophoblast Cell Culture Model to Study the Protective Effects of Melatonin Against Hypoxia/reoxygenation-induced Disruption
Published on: July 30, 2016
Melatonin influences on the neuroendocrine-reproductive axis
Beatriz Díaz López1, E Díaz Rodríguez, Colmenero Urquijo
1Departamento de Biología Funcional, Area Fisiología, Facultad de Medicina, Universidad de Oviedo. C /Julián Clavería, 6. 33006 Oviedo, Spain. beatrizd@uniovi.es
Abstract:
The neuroendocrine-reproductive axis designates the functional activity of the hypothalamus-pituitary-gonadal axis. A delicate synchronization of many inputs at these three different levels is vital for normal reproductive function. From the median basal hypothalamus, the median eminence releases gonadotrophin releasing hormone into the portal circulation to reach the anterior pituitary gland. Gonadotrophin releasing hormone is obviously a key hormone for the regulation of the secretion of gonadotrophins LH and FSH.
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