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Updated: Aug 13, 2026
Surgical Technique for the Implantation of a Biomimetic Artificial Intervertebral Disc in a Goat Animal Model
Published on: October 10, 2025
[Experimental study on distraction osteogenesis for reconstruction of maxillary defects with replacement of
Guo-fang Shen1, Xiao-hu Zhang, Xiao-feng Lu
1Department of Oral and Maxillofacial Surgery, School of Stomatology; Ninth People's Hospital, School of Medicine, Shanghai Jiao Tong University, China.
Purpose:
This study was aimed to set up a new method for reconstruction of maxillary defect with distraction osteogenesis through an animal experiment.
Methods:
11 adult goats were randomly divided into 2 groups (9 in the experimental group and 2 in the control group) in this study. 3 subgroups were set up in the experimental group based on the consolidation period. Other 2 goats were chosen as the control group. Maxillary defect was made firstly through partial maxillectomy for the experimental group. Length of the defects was from 12 to 14mm with an average of 12.7mm. A transport disc was then made through anterior Le Fort I osteotomy and it would be shifted backward for the closure of the defect. Only maxillary defect was made for the control group. Distraction was activated after a latency of 7 days at a rate of 0.4mm twice a day for 15-18 days.
Results:
Bone defects in the maxilla were well repaired when the transport disc was distracted back to its original position. Radiology and histology demonstrated good new bone formation in the distraction gap.
Conclusions:
Transport distraction osteogenesis would be a reasonable method for reconstruction of maxillary defect.
