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Bolus dose with continuous infusion of midazolam as sedation for outpatient surgery
N H Luyk1, M Zacharias, S Wanwimolaruk
1University of Otago, Dunedin, New Zealand.
Abstract:
This double-blind, randomised, cross-over trial in 41 patients for 3rd molar surgery compared the safety, amnesic properties and psychomotor recovery between a bolus injection of midazolam and a bolus injection followed by continuous infusion of midazolam. The latter showed good safety and better amnesia to events during the procedure, but prolonged the recovery time.