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Solid Lipid Nanoparticles (SLNs) for Intracellular Targeting Applications
08:19

Solid Lipid Nanoparticles (SLNs) for Intracellular Targeting Applications

Published on: November 17, 2015

A novel approach based on lipid nanoparticles (SLN) for topical delivery of alpha-lipoic acid

E B Souto1, R H Müller, S Gohla

  • 1Department of Pharmaceutical Technology, Biotechnology and Quality Management, The Free University of Berlin, Berlin, Germany.

Journal of Microencapsulation
|January 13, 2006
PubMed

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After oral administration, poor permeability often limits the rate at which drugs are absorbed through the intestinal epithelium. Enhancing drug permeability is crucial for effective therapy, and several strategies have been developed to overcome this challenge.One effective strategy involves the use of lipid-based formulations. These formulations enhance dissolution and solubility, targeting physiological mechanisms to increase drug absorption. This includes stimulating bile salt secretion,...