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Association between protein intake and blood pressure: the INTERMAP Study.

Paul Elliott1, Jeremiah Stamler, Alan R Dyer

  • 1Department of Epidemiology and Public Health, Faculty of Medicine, St Mary's Campus, Imperial College London, London, England. p.elliott@imperial.ac.uk

Archives of Internal Medicine
|January 13, 2006
PubMed
Summary

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Higher vegetable protein intake is linked to lower blood pressure. This supports dietary recommendations for preventing hypertension and related conditions.

Area of Science:

  • Nutritional Epidemiology
  • Cardiovascular Health
  • Dietary Protein

Background:

  • Epidemiological studies suggest a link between protein consumption and blood pressure.
  • Understanding the specific roles of different protein sources in blood pressure regulation is crucial.

Purpose of the Study:

  • To investigate the association between vegetable and animal protein intake and blood pressure.
  • To determine if protein source modifies the relationship between protein intake and hypertension.

Main Methods:

  • Cross-sectional study of 4680 adults (40-59 years) across four countries.
  • Multiple measurements of blood pressure and dietary intake via 24-hour recalls.
  • Analysis adjusted for various confounders, including height and weight.

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Main Results:

  • A significant inverse relationship was observed between vegetable protein intake and both systolic and diastolic blood pressure.
  • Higher vegetable protein intake (2.8% kilocalories) was associated with reduced blood pressure, even after adjustments.
  • Animal protein intake did not show a persistent significant association with blood pressure after adjustments.

Conclusions:

  • Increased vegetable protein consumption is inversely associated with blood pressure.
  • Dietary patterns rich in vegetable protein may contribute to the prevention of hypertension.
  • Findings support public health recommendations for plant-based diets for cardiovascular health.